Clotilde Courau began her film career in 1990 in front of Jacques Doillon’s camera in Le petit criminel, a role that earned her a César nomination and the European Film Award for best actress in 1991. Four years later, it was Jean Becker’s Elisa who brought her two new nominations at Les César (best female hope and best actress in a supporting role). She also received the Romy Schneider Prize in 2000. With more than thirty films to her credit, Clotilde has shot for great directors: Guillaume Nicloux (Le Poulpe), Guillaume Canet (Mon idole), Philippe Garrel (L'Ombre des femmes), Marie-Castille Mention-Schaar (Le Ciel attendra), Rebecca Zlotowski (Une fille facile) or Paul Verhoeven (Benedetta).
In 2017, she participated in Les Arcs Film Festival as a member of the Jury under the presidency of Céline Sciamma.